Fig. 2

Fibrosis after multiple cardiotoxin injections in mTG mice. a Hydroxyproline measurement in mTG mice 3 weeks after the third CTX injection; n = 3–4 per group; muscles from laminin α2-deficient (dy^w) and uninjected WT mice served as positive and negative controls, respectively; b, c Relative mRNA levels of pro-fibrotic genes at same the time point in PBS-injected muscles (b) and CTX-injected muscles (c); CTX-injured muscle gene expression levels were normalized to PBS levels of WT animals; n = 7–10 per group (t test); values are plotted as individual values or average ± SEM; *p ≤ 0.05, **p ≤ 0.01; Abbreviations: Col collagen