Fig 1

SC numbers, MRF expression, and SC proliferation after cardiotoxin injection. a SC numbers per area in TA (n = 4 per group), b SOL and EDL muscles (n = 4 per group) of mTGs and WTs. c Relative mRNA levels of Pax7 and MRFs in TA (n = 6 per group) of mTGs compared to controls (WT); mRNA levels in mTG were normalized to littermate control levels. d SC numbers per area 4 days post-CTX (n = 7–8 per group) and e 19 days post-CTX (n = 8–10 per group) in mTGs together with representative IHC images (laminin: green, DAPI/nuclei: blue; Pax7: red). Red rectangles denote enlarged areas of sections, and SCs are marked with white asterisks. Brightness/contrast was adjusted using ImageJ. Values are plotted as AV ± SEM; *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001