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Fig. 4 | Skeletal Muscle

Fig. 4

From: Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4

Fig. 4

The structures of PML bodies in a small fraction of nuclei were disrupted by DUX4-FL expression. Each row shows one myotube nucleus immunostained as indicated for DUX4-FL or PML along with a merged image. Dotted lines show the approximate outlines of each nucleus. In rows a–a” and b–b”, the arrows point to regions where PML staining appears to envelop DUX4-FL aggregates; and in rows c–c” and d–d”, the arrows point to PML staining that appears to be intertwined with small DUX4-FL aggregates. Bar in a = 10 μm

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Skeletal Muscle

ISSN: 2044-5040

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