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Fig. 7 | Skeletal Muscle

Fig. 7

From: Heme oxygenase and carbon monoxide protect from muscle dystrophy

Fig. 7

Delivery of carbon monoxide via small molecules protects against dystrophy. a Mice were treated daily with 2.5 mg/kg CORM-A1. b, c Sample Evans blue staining in diaphragm and % Evans blue extravasation in gastrocnemius (b) and serum creatine kinase (c) in mdx mice treated with CORM-A1 versus vehicle. d Relative expression of the indicated genes in gastrocnemius from mdx mice treated with CORM-A1 versus vehicle. e, f Fiber size distribution (e) and % central nuclei (f) in gastrocnemius muscle from mdx mice treated with CORM-A1 versus vehicle. n = 8. *P < 0.05, Student’s t test. Scale bar = 50 μm. Error bars indicate ±SEM

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