Fig. 4From: Voluntary resistance wheel exercise from mid-life prevents sarcopenia and increases markers of mitochondrial function and autophagy in muscles of old male and female C57BL/6J miceCitrate synthase activity in the quadriceps and gastrocnemius muscles of 15-month SED, 23-month SED, and 23-month RWE mice, of both sexes. Citrate synthase activity in the quadriceps (a) and gastrocnemius (b) muscle lysates was used as a marker of mitochondrial density. Data were analyzed by ANOVA, using age and sex and sex and activity as variables. Data are mean ± SEM. Asterisk denotes significance at *P < 0.05; **P < 0.01; ***P < 0.001. For each age group, N = 6–10 mice/groupBack to article page