Fig. 5
From: A novel method for the quantification of fatty infiltration in skeletal muscle
Fatty infiltration resulting from GLY injection is higher in the 129S1/Sv1mJ (129S1) mouse strain than in the C57BL/6J (BL/6J) mouse strain. a Images of ORO staining in decellularized muscles following GLY injection for three representative BL/6J muscles (upper panel) and three representative 129S1 muscles (lower panel). The location of the proximal vessel structure is indicated by the arrows. Global differences in both quantity and distribution of fatty infiltration are apparent between strains. Quantification of fatty infiltration metrics finds that b total lipid volume, c total number of adipocytes, d average adipocyte volume, e and the nearest neighbor index (a measure of spatial clustering) are significantly increased in the 129S1 muscle compared in the BL/6J. ***p < 0.0005