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Fig. 4 | Skeletal Muscle

Fig. 4

From: Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures

Fig. 4

DUX4 and PAX7 are expressed in distinct cell types during myogenic differentiation. Representative images of DUX4 positive cells from D40 of the differentiation protocol stained with antibodies to both PAX7 and DUX4. a hESC-FSHD, b hiPSC-mosaic1-short, c hiPSC-mosaic2-short, and d hiPSC-mosaic1-long showing PAX7 positive nuclei but no DUX4 signal. Bar graph quantifying the e percentage of DUX4 positive nuclei and f percentage of PAX7 positive nuclei for the given number of DAPI-stained nuclei

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