Skip to main content

Table 1 Human iPS and ES cell clone properties and D4Z4 array sizes

From: Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures

Cells

Allelea

Array status

bHaplotype

dD4Z4 (kb)

hESC-Cntrl

1

Non-pathogenic

c4qA161

91

2

Non-pathogenic

4qB168

44

3

Non-pathogenic

4qB168

67

hESC-FSHD

1

Non-pathogenic

4qA

135

2

Pathogenic

4qA

22

hiPSC-mosaic1-long

1

Non-pathogenic

4qA161

107

2

Non-pathogenic

4qB163

89

hiPSC-mosaic1-short

1

Pathogenic

4qA161

19

2

Non-pathogenic

4qB163

89

hiPSC-mosaic2-long

1

Non-pathogenic

4qA161

220

2

Non-pathogenic

4qA

70

hiPSC-mosaic2-short

1

Pathogenic

4qA161

15

2

Non-pathogenic

4qA

70

  1. aChromosome 4 allele
  2. bA (permissive) or B (non-permissive) and SSLP length
  3. cA161 allele is a hybrid of 4 and 10 type arrays
  4. d EcoRI fragment size for D4Z4 array on chromosome 4 in kilobase pairs