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Fig. 2 | Skeletal Muscle

Fig. 2

From: Exome sequencing reveals independent SGCD deletions causing limb girdle muscular dystrophy in Boston terriers

Fig. 2

Loss of SGC staining in cases 3 and 4. Representative H&E and immunofluorescence of cryosections from the muscle of cases 3 and 4, as well as of a control dog muscle. In the control muscle, antibodies to the SGC (α-, β-, δ-, γ-sarcoglycans: αSG, βSG, δSG, γSG), as well as sarcospan (SSPN), localize to the sarcolemma of the muscle fibers. Staining from each of these antibodies is reduced in muscle from cases 3 and 4

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Skeletal Muscle

ISSN: 2044-5040

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