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Fig. 3 | Skeletal Muscle

Fig. 3

From: Exome sequencing reveals independent SGCD deletions causing limb girdle muscular dystrophy in Boston terriers

Fig. 3

Representative immunofluorescence of cryosections from muscle of cases 3 and 4 and control dog muscle. Staining of α-dystroglycan (αDG), β-dystroglycan (βDG), dystrophin (DMD), caveolin 3 (CAV3), collagen VI (COL6), and perlecan (PCAN) in cases 3 and 4. Antibodies to α- and β-dystroglycans, dystrophin, caveolin 3, and perlecan demonstrate sarcolemmal localization and intensity that is comparable to control tissue. An antibody to collagen VI shows increased localization to the endomysium compared to the control tissue, consistent with endomysial fibrosis

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Skeletal Muscle

ISSN: 2044-5040

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