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Fig. 2 | Skeletal Muscle

Fig. 2

From: Differential requirement for satellite cells during overload-induced muscle hypertrophy in growing versus mature mice

Fig. 2

Satellite cell-mediated myonuclear accretion is prevented in satellite cell-depleted (SC-) but not satellite cell-replete (SC+) mice after synergist ablation overload of the plantaris for 10 days (OV). a–d Representative image of myonuclei per fiber length after OV in a young SC+, b mature SC+, c young SC-, d and mature SC- mice; scale bar=20 μm. e Myonuclei per 100 mm in young sham (n = 6 SC+, n = 5 SC-) and OV (n = 6 SC+, n = 6 SC-) mice. f Myonuclei per 100 mm in mature sham (n = 9 SC+, n = 7 SC-) and OV (n = 6 SC+, n = 7 SC-) mice. *p < 0.05 compared to respective sham

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