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Fig. 3 | Skeletal Muscle

Fig. 3

From: Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass

Fig. 3

Phosphorylation and total protein involved in protein synthesis in the gastrocnemius and soleus of bGH (n = 9) and WT (n = 9) mice. mTOR phosphorylation and mTOR total protein in the gastrocnemius (a) and soleus (b) of WT and bGH mice. Phosphorylation of 4E-BP1 and 4E-BP1 total protein in the gastrocnemius (c) and soleus (d) of WT and bGH mice. p70 S6 kinase phosphorylation and p70 S6 kinase total protein in the gastrocnemius (e) and soleus (f) of WT and bGH mice. Values in A.U. were normalized to a control sample run on each blot and then presented relative to GAPDH. Data are expressed as mean ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001 vs. WT control mice

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