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Fig. 4 | Skeletal Muscle

Fig. 4

From: Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass

Fig. 4

MAPK phosphorylation and protein content in gastrocnemius and soleus of bGH and WT mice. Phosphorylation of p42 and total p42 in the gastrocnemius (a) and the soleus (b) of WT and bGH mice. p44 phosphorylation and p44 total protein in the gastrocnemius (c) and soleus (d) of WT and bGH mice. Phosphorylation of p38 and total p38 in the gastrocnemius (e) and the soleus (f) of WT and bGH mice JNK2 phosphorylation and JNK2 total protein in the gastrocnemius (g) and the soleus (h) of WT and bGH mice. Values in A.U. were normalized to a control sample run on each blot and then presented relative to GAPDH. Data are expressed as mean ± SEM. * P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.0005 vs WT control mice. bGH (n = 9) and WT (n = 9) for each protein with the exception of (c) gastrocnemius p44 phosphorylation and p44 total protein (n = 7 in each group)

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