Fig. 1
From: Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle
Muscle architecture and dystrophin and utrophin expression in extensor digitorum longus (EDL) muscles from C57BL/10, mdx, dko and mdx-Fiona mice. Representative images of (a) muscle architecture (assessed by H&E staining), (b) utrophin (UTR) immunofluorescence, (c) dystrophin (DYS) immunofluorescence and (d) membrane integrity (assessed via IgG infiltration and indicated by green) of EDL muscle cross-sections from C57BL/10 (C57), mdx, dko and mdx-Fiona (mdx-Fio) mice (n = 5–6/group). Protein expression levels, detected by western blot, of (e) dystrophin and (f) utrophin in quadriceps muscles of C57, mdx, dko and mdx-Fio mice and corresponding loading control (total protein stain; TPS; each lane contains 3 pooled samples from each genotype)