Fig. 4

Different combinatorial landscapes result in different degrees of stringency for the list of genes defining the quiescent state of satellite cells. a Barplot indicating the number of overlapping differentially expressed genes (DEGs) for each best combination of intersections, from degree 2 to 11. The dots underneath the barplot indicate the datasets included in the intersections. The total number of up (UP) and down (DOWN) DEGs for each dataset are indicated in light gray and dark gray, respectively. Panels b and c are the colored matrices showing the Jaccard index between each pair of datasets, for UP DEGs and DOWN DEGs, respectively. Dendrograms show the hierarchical clustering using the Jaccard index as Euclidean distance