| |
Baseline
|
4 weeks
|
12 weeks
|
|---|
|
Number per square millimeter
|
Diameter (μm)
|
Number per square millimeter
|
Diameter (μm)
|
Number per square millimeter
|
Diameter (μm)
|
|---|
|
CAPN3-KO
|
|
STO
|
158
|
31.16 ± 0.4
|
647
|
23.1 ± 0.3****
|
633
|
24.1 ± 0.3****
|
|
FTG/O
|
316
|
40.81 ± 0.4
|
240
|
28.8 ± 0.6
|
153
|
35.8 ± 0.9**
|
|
All fibers
|
474
|
37.92 ± 0.3
|
887
|
24.6 ± 0.3****
|
786
|
26.4 ± 0.3****
|
|
Wild Type
|
|
STO
|
132
|
36.92 ± 0.5
|
466
|
26.2 ± 0.4
|
321
|
29.9 ± 0.4
|
|
FTG/O
|
230
|
45.35 ± 0.4
|
256
|
29.9 ± 0.6
|
183
|
39.6 ± 0.7
|
|
All fibers
|
362
|
42.27 ± 0.4
|
724
|
27.5 ± 0.3
|
504
|
33.3 ± 0.4
|
-
****
P < 0.0001 compared to same wild type parameter
- **P < 0.01 compared to same wild type parameter
