Impaired regeneration in calpain-3 null muscle is associated with perturbations in mTORC1 signaling and defective mitochondrial biogenesis

Table 2 Tibialis anterior muscle fiber size in CAPN3-KO mice following gene therapy

CAPN3-KO	Untreated-TA		AAV.CAPN3.wt-treated TA
CAPN3-KO	Number per square millimeter	Diameter (μm)	Number per square millimeter	Diameter (μm)
STO	355	32.72 ± 0.4	223	39.81 ± 0.6^****
FTG/O	116	44.26 ± 0.9	99	50.40 ± 1.2^****
All fibers	471	35.55 ± 0.4	322	43.08 ± 0.6^****

ISSN: 2044-5040