Skip to main content
Fig. 5 | Skeletal Muscle

Fig. 5

From: Development of the excitation-contraction coupling machinery and its relation to myofibrillogenesis in human iPSC-derived skeletal myocytes

Fig. 5

Depolarization-induced Ca2+ transients in differentiating human iPSC-derived skeletal myocytes. A Fura-2 ratiometric (340/380) fluorescence reflecting changes in intracellular Ca2+ level during 180 s of membrane depolarization by 50 mM extracellular [K+]. Symbols represent mean data (± SEM) obtained at different times post-differentiation as indicated (M: mature stages > 3 weeks post-differentiation). B–D Mean values (± SEM) of the three different characteristics of the Ca2+ signal at different times post-differentiation. Note that the value of time to peak was not included for day 4 (NA) as the signal has not reached a single peak profile necessary for this measurement

Back to article page

Skeletal Muscle

ISSN: 2044-5040

Contact us