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Fig. 3 | Skeletal Muscle

Fig. 3

From: Diversification of the muscle proteome through alternative splicing

Fig. 3

Tissue-specific regulation of pre-mRNA splicing. During myogenesis, induced expression of RBFOX1 and RBFOX2, which binds to the consensus downstream intronic element, promotes the production of the Mef2Dα2 alternative spliced variant. MEF2Dα2 facilitates the expression of late differentiation genes to support the formation of myotubes

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