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Fig. 3 | Skeletal Muscle

Fig. 3

From: A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses

Fig. 3

a–d Pedigrees from four subsets of the larger pedigree (Additional file 2: Figure S1) demonstrating a founder effect of four stallions for the IMM phenotype. Circles = females, squares = males. Open circles = phenotype unknown. Colored circles = IMM-affected with red = G/G genotype, blue = G/A genotype, and gray = A/A phenotype. Two of these founder stallions were traced back to the stallion in family A within one to three generations. For family D, the dam line traced back to the stallion in family A within four generations (Additional file 2: Figure S1)

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