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Fig. 2 | Skeletal Muscle

Fig. 2

From: Skeletal, cardiac, and respiratory muscle function and histopathology in the P448Lneo− mouse model of FKRP-deficient muscular dystrophy

Fig. 2

Inflammation levels (foci/mm2) in P448Lneo− (FKRP) mice gastrocnemius (panel a), quadriceps (panel b), and triceps (panel c) at 1, 2, 6, and 9 months of age compared to controls (BL6) and serum creatinine kinase (CK) at 9 months of age (panel d). Significant increases in inflammation are seen with a peak at 2 months of age. Serum CK levels are significantly increased at 1, 6, and 9 months. Data presented as mean ± standard deviation;*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001 using t test when compared to BL6 control mice at same age; ###p < 0.001 using two-tailed Mann-Whitney nonparametric test when compared to BL6 control mice at same age

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Skeletal Muscle

ISSN: 2044-5040

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