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Table 1 Timeline of experimental procedures performed on groups A, B, C, D of P448Lneo− and control mice. Groups A, B, and D were composed of P448Lneo− (n = 8) and control (n = 8) mice. Group C was composed of P448Lneo− (n = 8), exercised P448Lneo− (n = 12), and control (n = 8) mice. Group A was studied at 1 month of age. Group B was studied at 2 months of age. Group C was studied every month until age 6 months of age. A group of P448Lneo− mice underwent exercise treadmill running until 6 months of age. Control mice did not undergo exercise testing. Group D was studied until 9 months of age

From: Skeletal, cardiac, and respiratory muscle function and histopathology in the P448Lneo− mouse model of FKRP-deficient muscular dystrophy

Group

A

B

C

D

Timeline (months of age)

1

2

1

2

3

4

5

6

9

Treadmill exercise (2×/week only P448Lneo mice)

  

x

x

x

x

x

x

 

Body weight

x

x

x

x

x

x

x

x

x

Grip strength test

  

x

x

x

x

x

x

x

Digiscan activity

  

x

x

x

x

x

x

x

Echocardiography

   

x

   

x

x

Plethysmography

   

x

   

x

x

Serum creatinine kinase

x

x

     

x

x

Histology

x

x

     

x

x

Fibrosis

x

x

     

x

x