Table 2 Body, muscle, and organ weights normalized by body weight in P448Lneo− (FKRP) and control (BL6) mice showing significant differences at 6 and 9 months of age
Weight (n = 8) | 1 month | 2 months | 6 months | 9 months | ||||
|---|---|---|---|---|---|---|---|---|
BL6 | FKRP | BL6 | FKRP | BL6 | FKRP | BL6 | FKRP | |
Body (g) | 19 ± 1.2 | 19.6 ± 0.9 | 21.9 ± 1.5 | 22.3 ± 0.83 | 28 ± 1.7 | 30 ± 1.2 | 33 ± 6.0 | 31 ± 1.7 |
GAS/BW(10−6) | 6.2 ± 0.5 | 6.3 ± 0.3 | 6.4 ± 0.4 | 6.5 ± 0.4 | 5.4 ± 1 | 6.0 ± 0.2*** | 5.0 ± 0.2 | 6.3 ± 0.5*** |
Sol/BW(10−7) | 3.7 ± 0.3 | 3.7 ± 0.2 | 3.8 ± 0.9 | 3.6 ± 0.5 | 3.0 ± 0.4 | 3.5 ± 0.2* | 3.3 ± 0.3 | 4.1 ± 0.4** |
TA/BW(10−6) | 2.4 ± 0.4 | 2.3 ± 0.2 | 2.3 ± 0.1 | 2.3 ± 0.2 | 1.8 ± 0.2 | 2.2 ± 0.2*** | 1.4 ± 0.2 | 2.0 ± 0.3*** |
Triceps/BW(10−6) | 4.1 ± 0.4 | 4.4 ± 0.4 | 4.4 ± 0.6 | 4.3 ± 0.4 | 3.4 ± 0.6 | 4.5 ± 0.3*** | 3.3 ± 0.6 | 5.4 ± 0.9*** |
Quad/BW(10−6) | 7.0 ± 0.2 | 7.3 ± 1.1 | 5.7 ± 0.8 | 6.0 ± 0.8 | 5.3 ± 0.8 | 6.5 ± 0.9* | 5.0 ± 0.9 | 6.3 ± 0.4** |
Heart/BW(10−6) | 5.0 ± 0.2 | 5.3 ± 0.5 | 5.1 ± 0.2 | 5.2 ± 0.4 | 4.3 ± 0.3 | 4.4 ± 0.2 | 3.9 ± 0.5 | 4.4 ± 0.4* |
Brain/BW(10−6) | 21 ± 1.2 | 20 ± 3.6 | 20 ± 1.4 | 19 ± 1 | 16 ± 1.2 | 15 ± 0.5* | 14.5 ± 2.8 | 14.2 ± 0.1 |