Table 3 Body, muscle, and organ weights normalized by body weights among groups of P448Lneo− (FKRP) without and with treadmill exercise (FKRP-treadmill) and control (BL6) mice at 6 months of age
Measurement | BL6 control | FKRP | FKRP-treadmill | Significantly different groups (adjusted p values using ANOVA followed by post hoc analysis) | |||
|---|---|---|---|---|---|---|---|
N | Mean ± SD | N | Mean ± SD | N | Mean ± SD | ||
Body (g) | 8 | 28 ± 1.7 | 8 | 30 ± 1.2 | 12 | 29 ± 1.8 | NS |
GAS/BW(10−6) | 8 | 5.4 ± 0.3 | 8 | 6.0 ± 0.2 | 12 | 6.4 ± 0.7 | BL6 vs FKRP: p < 0.05, BL6 vs FKRP-treadmill: p < 0.001 |
Sol/BW(10−7) | 8 | 3.0 ± 0.4 | 8 | 3.5 ± 0.2 | 12 | 3.4 ± 0.3 | BL6 vs FKRP: p < 0.05, BL6 vs FKRP-treadmill: p < 0.05. |
TA/BW(10−6) | 8 | 1.8 ± 0.2 | 8 | 2.2 ± 0.2 | 12 | 2.4 ± 0.3 | BL6 vs FKRP: p < 0.01, BL6 vs FKRP-treadmill: p < 0.001 |
Triceps/BW(10−6) | 8 | 3.4 ± 0.6 | 8 | 4.5 ± 0.3 | 12 | 5.2 ± 0.7 | BL6 vs FKRP: p < 0.01, BL6 vs FKRP-treadmill: p < 0.0001 FKRP vs FKRP-treadmill: p < 0.05 |
Quad/BW(10−6) | 8 | 5.3 ± 0.8 | 8 | 6.5 ± 0.9 | 12 | 7.0 ± 1.3 | BL6 vs FKRP: p < 0.05, BL6 vs FKRP-treadmill: p < 0.01 |
Heart/BW(10−6) | 8 | 4.3 ± 0.3 | 8 | 4.4 ± 0.2 | 12 | 4.4 ± 0.5 | NS |
Brain/BW(10−6) | 8 | 16 ± 1.2 | 8 | 15 ± 0.5 | 12 | 16 ± 1.2 | NS |