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Table 3 Body, muscle, and organ weights normalized by body weights among groups of P448Lneo (FKRP) without and with treadmill exercise (FKRP-treadmill) and control (BL6) mice at 6 months of age

From: Skeletal, cardiac, and respiratory muscle function and histopathology in the P448Lneo− mouse model of FKRP-deficient muscular dystrophy

Measurement BL6 control FKRP FKRP-treadmill Significantly different groups (adjusted p values using ANOVA followed by post hoc analysis)
N Mean ± SD N Mean ± SD N Mean ± SD
Body (g) 8 28 ± 1.7 8 30 ± 1.2 12 29 ± 1.8 NS
GAS/BW(10−6) 8 5.4 ± 0.3 8 6.0 ± 0.2 12 6.4 ± 0.7 BL6 vs FKRP: p < 0.05,
BL6 vs FKRP-treadmill: p < 0.001
Sol/BW(10−7) 8 3.0 ± 0.4 8 3.5 ± 0.2 12 3.4 ± 0.3 BL6 vs FKRP: p < 0.05,
BL6 vs FKRP-treadmill: p < 0.05.
TA/BW(10−6) 8 1.8 ± 0.2 8 2.2 ± 0.2 12 2.4 ± 0.3 BL6 vs FKRP: p < 0.01,
BL6 vs FKRP-treadmill: p < 0.001
Triceps/BW(10−6) 8 3.4 ± 0.6 8 4.5 ± 0.3 12 5.2 ± 0.7 BL6 vs FKRP: p < 0.01,
BL6 vs FKRP-treadmill: p < 0.0001
FKRP vs FKRP-treadmill: p < 0.05
Quad/BW(10−6) 8 5.3 ± 0.8 8 6.5 ± 0.9 12 7.0 ± 1.3 BL6 vs FKRP: p < 0.05,
BL6 vs FKRP-treadmill: p < 0.01
Heart/BW(10−6) 8 4.3 ± 0.3 8 4.4 ± 0.2 12 4.4 ± 0.5 NS
Brain/BW(10−6) 8 16 ± 1.2 8 15 ± 0.5 12 16 ± 1.2 NS
  1. GAS gastrocnemius, Sol soleus, TA tibialis anterior, Quad quadriceps, BW body weight, NS not significant