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Fig. 6 | Skeletal Muscle

Fig. 6

From: Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats

Fig. 6

Mitochondrial content and mitochondrial oxygen consumption rate (OCR) in skeletal muscle of the experimental groups. a SDH staining was performed on 10-μm-thick sections from gastrocnemius muscles frozen in liquid nitrogen-cooled isopentane. Scale bar 50 μm. b Quantification of SDH-stain intensity (expressed in A.U). c Mitochondrial yield in isolated quadriceps muscles. d The mitochondrial oxygen consumption rate (OCR) in isolated quadriceps muscles. Results are presented as the mean ± SD, n = 6 per group. Mean value was significantly different from that of the sham group: *P < 0.05, **P < 0.01. Mean value was significantly different from that of the NPD group: †P < 0.05, ††P < 0.01. Mean value was significantly different from that of the LPD group: ‡P < 0.05. Sham, normal-protein diet; NPD, normal-protein diet; LPD, low-protein diet; LPD + KA, low-protein diet supplemented with ketoacids

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