Skip to main content
Fig. 7 | Skeletal Muscle

Fig. 7

From: Dietary supplementation with ketoacids protects against CKD-induced oxidative damage and mitochondrial dysfunction in skeletal muscle of 5/6 nephrectomised rats

Fig. 7

Expression of p66Shc and FoxO3a mRNA, and proteins in the skeletal muscle of the experimental groups. a p66Shc and b FoxO3a mRNA expression was measured by RT-PCR and is presented as corrected for GAPDH and normalised to the sham group. c Upper: representative immunoblotting of p66Shc and GAPDH. Lower: the ratio of p66Shc and GAPDH normalised to the sham group. d Upper: representative immunoblotting of FoxO3a and GAPDH. Lower: the ratio of FoxO3a and GAPDH normalised to the sham group. Results are presented as the mean ± SD, n = 6 per group. Mean value was significantly different from that of the sham group: *P < 0.05, **P < 0.01. Mean value was significantly different from that of the NPD group: †P < 0.05, ††P < 0.01. Mean value was significantly different from that of the LPD group: ‡P < 0.05. Sham, normal-protein diet; NPD, normal-protein diet; LPD, low-protein diet; LPD + KA, low-protein diet supplemented with ketoacids

Back to article page