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Table 3 EM analysis of EDL from WT and MAP6 KO

From: Deletion of the microtubule-associated protein 6 (MAP6) results in skeletal muscle dysfunction

   WT KO
A Fibers with SR membrane stacks (% of total) 23.5 ± 3.5 64.0 ± 4.4**
B N. of SR stacks /100 μm2 3.4 ± 0.6 10.6 ± 0.9**
C Free SR volume/total volume (%) 5.3 ± 0.4 6.5 ± 0.3**
D Free SR surface area/total volume (μm2/μm3) 1.2 ± 0.1 1.5 ± 0.1*
  1. Data are shown as mean ± SEM. Student’s t test, *p < 0.05 and **p < 0.01 vs WT. Sample size: rows A and B: 20–30 fibers, 2 micrographs/fiber (22,000 magnification images in transversal sections); rows C and D: 30–45 fibers; 5 micrographs/fiber (28,000 magnification images in transversal sections)