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Fig. 1 | Skeletal Muscle

Fig. 1

From: Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

Fig. 1

Body weights, muscle weights, serum drug concentrations, and morphometric analysis from a 4-week C57BL/6 mouse study. a Body weights from dosing of FS-EEE-mFc. b Muscle weights from dosing of FS-EEE-mFc. c Drug concentrations of FS-EEE-mFc from serum samples taken immediately prior to dosing. d Body weight changes at day 28 from dosing of FS-EEE-hFc. e Muscle weights from dosing of FS-EEE-hFc. f Quadriceps morphometric analysis by Oregon Green® 488 WGA staining of quadriceps. g Histogram of myofiber diameters. *p < 0.05 compared to vehicle-dosed group as described in the “Methods” section

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Skeletal Muscle

ISSN: 2044-5040

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