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Fig. 2 | Skeletal Muscle

Fig. 2

From: Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

Fig. 2

Body weights, muscle weights, muscle fiber size, grip strength, and serum biomarkers from a 12-week unexercised mdx study. a Body weights. b Muscle weights. c Quadriceps rectus femoris area. d Oregon Green® 488 WGA staining of quadriceps, example from the vehicle group. e Quadriceps morphometric analysis histogram of myofiber diameter size distribution. f Forelimb grip strength: (left) absolute and (right) normalized to body weight. g Serum biomarkers: (left) creatine kinase, (middle) skeletal troponin 1, (right) cardiac troponin 1. *p < 0.05 compared to mdx vehicle-dosed group as described in the “Methods” section

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Skeletal Muscle

ISSN: 2044-5040

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