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Fig. 5 | Skeletal Muscle

Fig. 5

From: Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

Fig. 5

Body weights, tissue weights, functional measurements, behavioral measurements, and serum analyses from a 12-week exercised mdx study. a Body weights. b Muscle weights. c Organ weights. d Forelimb grip strength (top) and normalized to body weight (bottom). e Ex vivo force of EDL muscle (top) and normalized to cross-sectional area (bottom). f Forced treadmilling distance (top) and normalized to body weight (bottom). g Serum creatine kinase. h. Serum drug concentrations sampled at day 56. *p < 0.05 compared to mdx vehicle-dosed group as described in the “Methods” section

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