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Fig. 6 | Skeletal Muscle

Fig. 6

From: Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

Fig. 6

Quadriceps tissue analysis from a 12-week exercised mdx study. (A-C) Representative images from the (top) vehicle control and (middle) 30 mg/kg FS-EEE-mFc and (bottom) total slide image analysis for a mouse IgG-positive staining for necrosis, b CD68-positive staining for macrophage infiltration, and c collagen I-positive staining for fibrosis. d qPCR of fibrosis and inflammation markers. *p < 0.05 compared to mdx vehicle-dosed group as described in the “Methods” section

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Skeletal Muscle

ISSN: 2044-5040

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