Fig. 2
From: The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis
Deleting ZFP36L1 and ZFP36L2 in Pax7-expressing cells reduces the number of satellite cells in TA muscles. Transverse cross sections from 3- to 4-week-old Zfp36L1/L2-P and control mice. Controls represent Cre-negative littermates. a Sections were immunostained with antibodies against Pax7 (red), a marker of adult satellite cells, laminin (green), an extracellular matrix protein to delineate the periphery of the individual muscle fibres, and with DAPI (blue), a nuclear marker. Open arrows indicate Pax7+ cells. Scale bars: 100 μm. b Average number of satellite cells in TAs from control and Zfp36L1/L2-P mice. Error bars represent SEM, significance measured by unpaired two-tailed Student’s t test, n = 3. Calculations from 10 fields of view per experiment