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Fig. 5 | Skeletal Muscle

Fig. 5

From: Late-onset megaconial myopathy in mice lacking group I Paks

Fig. 5

Analysis of mitochondrial protein expression and respiratory complex function. a Western blot analysis of mitochondrial proteins in quadriceps muscle extracts from 1-year-old control and dKO mice. Gapdh was used as a loading control. Three mice of each genotype are shown. The arrows indicate Drp and pDrp bands; the bands below are non-specific. b Densitometric quantification of the results in a; Gapdh was used for normalization. c Quantitative analysis of mitochondrial respiratory chain complexes I, II, and IV activity of the hindlimb muscle. n = 3 mice per genotype, *p < 0.05

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