Fig. 1From: RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathyPCA and heat map of DEGs of muscle samples from ICU patients and healthy controls. a PCA of TA skeletal muscle samples from healthy control subjects and ICU patients with CIM using all genes (RPKM log2 transformed and mean centered) b Heat map of top 1266 DEGs between ICU patients with CIM and healthy control muscle samples (independent group t test p < 0.05 and fold difference ≥ 3). RPKM of each gene was normalized against the mean of healthy controls and followed by log2 transformationBack to article page