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Fig. 2 | Skeletal Muscle

Fig. 2

From: RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathy

Fig. 2

Ingenuity upstream regulator analysis of top skeletal muscle genes perturbed in ICU patients with CIM. The most significantly perturbed genes in the ICU patients with CIM (361 genes, Student t test p < 0.05 and fold change > 5 in either directions) were subjected to the analysis. Inclusion criteria were p < 1.0E−04 and activation z-score > 2

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