Fig. 2From: RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathyIngenuity upstream regulator analysis of top skeletal muscle genes perturbed in ICU patients with CIM. The most significantly perturbed genes in the ICU patients with CIM (361 genes, Student t test p < 0.05 and fold change > 5 in either directions) were subjected to the analysis. Inclusion criteria were p < 1.0E−04 and activation z-score > 2Back to article page