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Fig. 5 | Skeletal Muscle

Fig. 5

From: Exogenous expression of the glycosyltransferase LARGE1 restores α-dystroglycan matriglycan and laminin binding in rhabdomyosarcoma

Fig. 5

Matriglycan levels in human eRMS and aRMS cell lines. ac Western blotting of WGA-enriched protein samples extracted from the human eRMS cell line Rh18 and the aRMS cell line Rh41 for core α-dystroglycan (a), matriglycan-modified α-dystroglycan (b), and laminin-bound dystroglycan (c). d Relative expression of mRNAs encoding dystroglycan (DAG1) and the dystroglycan-modifying glycosyltransferases in the Rh18 cell line, as assessed by real-time PCR. * These values are statistically different according to unpaired two-sample t test, p < 0.05

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