Table 1 EC₅₀ of BMPs and model parameters for the ALP activity of mrSCs isolated from control (Saline) and damaged (CTX) muscles

ALPmax

14.47 ± 0.23

29.25 ± 0.51

95.22 ± 0.44

164.98 ± 0.48

β

2.40 ± 0.06

0.64 ± 0.04

1.59 ± 0.03

1.80 ± 0.03

EC₅₀ (nM)

2.46 ± 0.07

1.71 ± 0.14

4.81 ± 0.02

1.03 ± 0.02

Minimum Effective Dose (nM)

1.0

0.05

1.0

0.01

R ²

0.9845

0.9591

0.9912

0.9884

p Value

< 0.001

< 0.001

< 0.001

< 0.001