Fig. 3

Infiltration of WT, miR-146a^−/−, mdx, and miR-146a^−/−mdx hind limb muscle with leukocytes, macrophages, monocytes, and granulocytes. a Semi-quantitative analysis of inflammation in GM muscle; HE staining; representative photos. b Percentage of CD45⁺F4/80⁺CD11b⁺ macrophages; flow cytometry. c Percentage of M1-like macrophages (CD45⁺F4/80⁺CD11b⁺MHCII^hiCD206^lo) and M2-like macrophages (CD45⁺F4/80⁺CD11b⁺MHCII^loCD206^hi); flow cytometry. d Percentage of monocytes (CD45⁺F4/80⁻CD11b⁺Ly6C⁺Ly6G⁻) and granulocytes (CD45⁺F4/80⁻CD11b⁺Ly6C⁺Ly6G⁻); flow cytometry. Mean +/− SEM; n = 4–10; *− p ≤ 0.05; ***− p ≤ 0.001. Scale bars 100 μm