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Fig. 1 | Skeletal Muscle

Fig. 1

From: Immunohistochemical phenotyping of T cells, granulocytes, and phagocytes in the muscle of cancer patients: association with radiologically defined muscle mass and gene expression

Fig. 1

SMI z-scores (SD, standard deviation) for male (n = 20, circles) and female (n = 10, diamonds) patients of the current study in relation to the SMI z-score distribution (dark gray histogram) from a cancer cohort with gastrointestinal tract and lung solid tumors (n = 1473, 58% males) from the same regional cancer center [13]. SMI z-scores were calculated based on sex and age [15]. Circle and diamonds in light gray are patients with highest values of CD8 T cells per 100 fibers. Vertical arrows representing SMI z-scores (SD) for healthy 30-year-old kidney donor candidates were placed to highlight cancer patient with SMI z-score values that are similar to the healthy population [61]. Notes: Only one SMI distribution is shown indistinctively of sex, as male (n = 828) and female (n = 645) SMI distribution shapes were the same in the Martin et al. cohort [13]. SMI z-scores for healthy kidney donor candidates were calculated by subtracting Martin et al. oncological cohort mean SMI values (males: 51.5 cm2/m2/females: 41.3 cm2/m2) from Derstine et al. healthy 30-year-old mean SMI values (males: 60.9 cm2/m2/females: 47.5 cm2/m2) and divided by the SD of Martin et al. oncological cohort (males: ± 8.9/females: ± 7)

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Skeletal Muscle

ISSN: 2044-5040

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