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Table 1 Patient characteristics

From: Immunohistochemical phenotyping of T cells, granulocytes, and phagocytes in the muscle of cancer patients: association with radiologically defined muscle mass and gene expression

 

All (n = 30)

Males (n = 20)

Females (n = 10)

p

Age, mean years ± SD (Min-Max)

64 ± 11 (38–81)

63 ± 13 (38–81)

67 ± 7 (52–77)

0.71

Tumor type, % (n)

   

0.68

 Colorectal

37 (11)

35 (7)

40 (4)

 

 Pancreas

30 (9)

25 (5)

40 (4)

 

 Liver

10 (3)

10 (2)

10 (1)

 

 Bile duct

7 (2)

10 (2)

0 (0)

 

 Gallbladder

7 (2)

5 (1)

10 (1)

 

 Others

9 (3)

15 (3)

0 (0)

 

Tumor stage, % (n)

   

0.22

 I

3.3 (1)

5 (1)

0 (0)

 

 II

3.3 (1)

5 (1)

0 (0)

 

 III

13 (4)

10 (2)

20 (2)

 

 IV

67 (20)

60 (12)

80 (8)

 

N/A

13.3 (4)

20 (4)

0 (0)

 

BMI (kg/m2), mean ± SD

27 ± 7

27 ± 6

26 ± 9

0.68

BMI classification, % (n)

   

0.24

 Underweight

10 (3)

10 (2)

10 (1)

 

 Normal

47 (14)

40 (8)

60 (6)

 

 Overweight

23 (7)

30 (6)

10 (1)

 

 Obesity I

7 (2)

5 (1)

10 (1)

 

 Obesity II

10 (3)

15 (3)

0 (0)

 

 Obesity III

3 (1)

0 (0)

10 (1)

 

Comorbidities, % (n)

    

 Diabetes type II

30 (9)

20 (4)

50 (5)

0.96

 Hypertension

50 (15)

50 (5)

50 (5)

1.00

 CVD

23 (7)

25 (5)

20 (2)

0.76

 Dyslipidemia

23 (7)

25 (5)

20 (2)

0.76

Computed tomography body composition analysis, mean ± SD

    

 L3 Muscle CSA (cm2)

132.1 ± 33.9

146.8 ± 29.5

102.6 ± 20.3

< 0.01*

 SMI (cm2/m2)

45.8 ± 9.2

49 ± 8.5

40.5 ± 8.4 *

0.39

 SMI z-score (SD)

−0.2 ± 1.1

−0.3 ± 1.1

−0.1 ± 1.2

0.59

 L3 Muscle radiodensity (HU)

30.8 ± 9.5

31.4 ± 10.5

30.4 ± 7.6

0.72

 L3 VAT CSA (cm2)

172.3 ± 91.9

188 ± 97.2

150.6 ± 79.7

0.29

 L3 SAT CSA (cm2)

192.8 ± 115.2

165.2 ± 110.7

247.5 ± 102.2

0.015*

 L3 TAT CSA (cm2)

377.1 ± 172.3

365.2 ± 173

409.5 ± 168.9

0.45

Muscle histological characteristics: Muscle fiber CSA (μm2), mean ± SD

3154 ± 1408

3707 ± 1329

2047 ± 788*

< 0.01*

  1. Others: melanoma, chronic lymphocytic leukemia, and lymphoma. N/A no applicable, BMI body mass index, CVD cardiovascular disease, L3 lumbar 3, CSA cross-sectional area, HU Hounsfield unit, VAT visceral adipose tissue, SAT subcutaneous adipose tissue, TAT total adipose tissue, SMI skeletal muscle index, SD standard deviation. *Difference between males and females (p = < 0.05)