Immunohistochemical phenotyping of T cells, granulocytes, and phagocytes in the muscle of cancer patients: association with radiologically defined muscle mass and gene expression

Table 5 Human studies reporting number of CD3+ (T cells) and CD11b+ (granulocytes/phagocytes) in muscle

Study	Subjects	Age (years)	Sample size	Muscle group	Number of CD3+/mm²	Number of CD11b+/mm²
Anoveros-Barrera et al. (current study)	Cancer population, men and women	64 (38–81)	n = 30	rectus abdominis	12.3 (1.6–33.3)	3 (0–13)
Pandya et al. [11]	Myopathy, men and women	64 (43–74)	n = 16	VA and TA	13.5 (0.5–963)	N/A
Dorph et al. [12]	Myopathy, men and women	58 (38–76)	n = 11	VA and TA	Symptomatic muscles: 58.1 (0.5–159.8) Asymptomatic muscles: 55.9 (1.1–126.8)	N/A
Dorph et al. [12]	Healthy volunteers, men and women	51 (47–56)	n = 6	VL and TA	1.8 (0.4–5.0)	N/A
Englund et al. [7]	Myopathy, men and women.	46 (26–64)	n = 11	VL	3 (0–7)	1 (0–10)
Englund et al. [7]	Healthy volunteers, men and women	27 (22–46)	n = 7	VL	1 (0–2)	0 (0–1)

Values reported as median (minimum-maximum). Myopathy: polymyositis and dermatomyositis. VL vastus lateralis, TA tibialis anterior, N/A not assessed

ISSN: 2044-5040