Fig. 1

BaCl₂ depolarizes skeletal muscle myofibers. a Representative continuous recording of V_m illustrates depolarization of mouse EDL myofiber upon exposure to 1.2% BaCl₂. b Summary data for V_m are at resting baseline, at peak depolarization during 1.2% BaCl₂ added to standard PSS and to PSS in which BaCl₂ replaced NaCl for osmotic (Osm) control. c Summary data for time to peak depolarization during 1.2% BaCl₂ added to standard PSS, and to PSS in which BaCl₂ replaced NaCl for Osm control. Values are means ± SEM (n = 3–6 myofibers, each from one EDL muscle per mouse). ^#P ≤ 0.05 vs. baseline