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Table 3 Alternative splicing analysis

From: Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity

Phenotype

Mouse ID*

#SE

#RI

ACTA1-MCM/+

MCM-1127

9619

1905

MCM-1246

9775

1934

MCM-1349

9890

1940

 

9761 ± 95

1926 ± 14

FLExD/+

FLExD-1358

9704

1910

FLExD-1367

9745

1913

FLExD-1378

9828

1934

 

9759 ± 46

1919 ± 10

 

p = 0.489896

p = 0.30383

Moderate model

dTGM-1236

10,987

2278

dTGM-1308

10,917

2261

dTGM-1331

10,940

2255

 

10,948 ± 26

2265 ± 9

 

p = 0.000064

p < 0.00001

Severe model

dTGS-1047

11,691

2505

dTGS-1066

11,658

2456

dTGS-1079

11,560

2466

 

11,636 ± 51

2476 ± 20

 

p = 0.000014

p < 0.00001

  1. p values calculated compared with ACTA1-MCM/+
  2. *Mouse ID correlates with RNA-seq data in Table S1