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Table 1 Characteristics of the mice in Protocol 2

From: Angiotensin-converting-enzyme inhibitor prevents skeletal muscle fibrosis in myocardial infarction mice

 

Sham + Veh

MI + Veh

MI + Lis

Total number

6

6

6

Body and organ weight

   

 BW, g

24.5 ± 0.3

25.0 ± 0.4

24.3 ±0.6

 Heart weight/BW, mg/g

4.4 ± 0.2

5.8 ± 0.3*

5.8 ± 0.3*

 Lung weight/BW, mg/g

5.5 ± 0.1

7.1 ± 0.7

6.4 ± 0.5

 Gastrocnemius weight/BW, mg/g

5.6 ± 0.1

5.4 ± 0.1

5.4 ± 0.1

Noninvasive blood pressure measurements

   

 SBP, mmHg

99 ± 2

95 ± 2

89 ± 3*

Serum angiotensin II, ng/mL

10.9 ± 2.0

26.2 ± 5.1*

4.0 ± 1.5*†

Skeletal muscle cross-sectional area, μm2

2269 ± 141

2028 ± 21

2100 ± 94

Grip strength, N

1.52 ± 0.03

1.53 ±0.04

1.58 ± 0.07

Spontaneous physical activity, count/day

2104 ± 416

1916 ± 410

2350 ± 281

  1. Data are expressed as the mean ± S.E.M. n = 6
  2. BW body weight, DBP diastolic blood pressure, Lis lisinopril, MI myocardial infarction, SBP systolic blood pressure, Veh vehicle
  3. *P < 0.05 vs. Sham + Veh, †P < 0.05 vs. MI + Veh