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Fig. 5 | Skeletal Muscle

Fig. 5

From: Functional effects of muscle PGC-1alpha in aged animals

Fig. 5

Skeletal muscle PGC-1alpha has little effect on whole-body metabolism in 24-month-old mice. a Glucose tolerance test (GTT) in male and female 24-month-old mice. Calculated AUC of GTTs. b Western blots for pAkt and Akt in quadriceps (quantification is normalized to loading control 14-3-3). c VO2, VCO2, and respiratory quotient (RER) in 24-month-old mice measured via Comprehensive Laboratory Animal Monitoring System (CLAMS). d Physical activity of 24-month-old mice measured via CLAMS [n = 5, 5 for 24-month-old WT and MCKa]. *P < 0.05 compared to control

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