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Fig. 1 | Skeletal Muscle

Fig. 1

From: SMN-deficiency disrupts SERCA2 expression and intracellular Ca2+ signaling in cardiomyocytes from SMA mice and patient-derived iPSCs

Fig. 1

Elevated expression of heart failure markers in SMA model mice. qRT-PCR analysis of a BNP and b ACTA1 mRNA expression. Expression levels (mean ± SEM) in SMN-deficient (SMA) heart tissue are represented relative to unaffected controls at each time point. Statistical analysis: p values shown for one-way ANOVA, Tukey’s post hoc test, n = 7

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