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Fig. 1 | Skeletal Muscle

Fig. 1

From: Pluripotent stem cell-derived skeletal muscle fibers preferentially express myosin heavy-chain isoforms associated with slow and oxidative muscles

Fig. 1

PSC-derived myogenic progenitors preferentially give rise to myofibers expressing oxidative MyHC isoforms. a Representative images show staining for MyHC isoforms (red) and dystrophin (green) in NSGmdx4cv. Nuclei were counterstained with DAPI (blue). Magnification bar, 100 μm. b Bar graphs show the percentage of DYS+MyHC+ double positive with respect to total donor-derived DYS+ myofibers. Data are shown as mean ± SEM (n = 7–8 per group). ***p < 0.001 and ****p < 0.0001. Adult, satellite cells from TAs of 3-month-old NSGmdx4cv mice

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Skeletal Muscle

ISSN: 2044-5040

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