Fig. 2
Fiber type composition of PSC-derived skeletal muscle is not dependent on the background of recipient muscles. a Representative images show staining for MyHC isoforms (red) and dystrophin (white) in TA muscles from NSG mice that had been injected with iPax3 or iPax7 myogenic progenitors. PBS served as control. Green nuclei represent epifluorescence of H2B-GFP. Nuclei were counterstained with DAPI (blue). Yellow boxes indicate position of the higher magnification insets below. Magnification bar, 100 μm. b Bar graphs show respective quantification (panel a). Percentages represent the ratio between the engraftment area (GFP) and MyHC expression, in comparison to PBS, represented as the percentage of total MyHC positive. Data are shown as mean ± SEM (n = 4 per group). **p < 0.05, ***p < 0.001, and ****p < 0.0001