Skip to main content
Fig. 4 | Skeletal Muscle

Fig. 4

From: X-linked muscular dystrophy in a Labrador Retriever strain: phenotypic and molecular characterisation

Fig. 4

Force and relaxation measurement in LRMD dogs at 4 and 6 months of age. Histograms represent mean value ± SD of healthy (white), GRMD (grey) or LRMD (black) populations. The black symbols represent the individual values of the two LRMD dogs studied (2 pelvic limbs measured for each animal). a Relative maximal tetanic force, at 4 and 6 months of age, obtained after normalisation by the leg length in order to account for differences in dog size. Muscle force was decreased in LRMD dogs compared to healthy dogs, and it was slightly reduced compared with GRMD dogs. b Post-tetanic residual contraction as a percentage of the tetanic force at 4 and 6 months of age, was measured by normalising the difference between pre- and post-tetanic baselines by the maximal tetanic force. An incomplete relaxation after a tetanic stimulation was observed in LRMD dogs as well as in GRMD dogs, with an increase of this relaxation defect with age

Back to article page