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Fig. 1 | Skeletal Muscle

Fig. 1

From: Exercise enhances mitochondrial fission and mitophagy to improve myopathy following critical limb ischemia in elderly mice via the PGC1a/FNDC5/irisin pathway

Fig. 1

The effects of exercise on the blood flow and functional recovery following CLI. a The perfusion of lower limbs in exercised and sedentary mice. b The ischemic/control blood flow of exercised mice (red line, n = 27) and sedentary mice (black line, n = 26) on different days. The results were displayed as means with standard derivation. The comparison of function (c) and necrosis scores (d) between exercised mice (red line, n = 27) and sedentary mice (black line, n = 26) was conducted. The results were shown as median (upper/lower limits). e The hematoxylin-eosin staining of four groups (n = 3 samples/group). Magnification × 400. f The comparison of cross-sectional area was used by ANOVA (n = 3 samples/group) and the comparison of quantification of fiber numbers was conducted by the Mann-Whitney U test (n = 3 samples/group). g The number of CD31-positive cells (indicated by the black arrowheads) was compared among four groups (n = 3 samples/group). Magnification × 200. h The Mann-Whitney U test was used to compare the difference in the number of CD31-positive cells among groups. *p < 0.05, **p < 0.01

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Skeletal Muscle

ISSN: 2044-5040

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